Linovera® Emulsion

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Linovera® Emulsion to fight chronic wounds

Chronic wounds are a major global medical concern,1 significantly impacting patients’ quality of life,2 while also affecting close family and relatives. Chronic wounds also cause considerable financial burden3 on the healthcare system and society.

Topical preventive measures such as Linovera® Emulsion are needed to avoid higher healthcare expenditures and preserve patients’ health. They can be used with the goal of promoting integrity of the skin and providing essential moisturizing.4

HOFA-containing topical formulations have become an ideal therapeutic option that is part of the clinical protocols for nursing action in the prevention and treatment of ulcers.5

Linovera® Emulsion is a light emulsion moisturizing cream composed of:

  • Hyperoxygenated fatty acids (HOFA) originated from sunflower oil naturally rich in linoleic acid,6 an essential fatty acid important in the maintenance of epidermal integrity and the natural skin’s water barrier.7 Some of the HOFA properties can increase skin resistance, reduce dehydration, reduce friction and pressure forces8 and improve microcirculation.9  
  • Vegetable extracts formulated to provide additional benefits such as skin conditioning, humectant and tonic, enhancing the activity of the product.

How Linovera® Emulsion can be used

Thanks to its content of HOFA and vegetable extracts, Linovera® Emulsion can be useful in the prevention of skin breakdown (e.g. pressure ulcers, vascular ulcers, and diabetic foot ulcers) or in the management of already impaired skin8,10 helping to provide the best care for your patients.

With its creamy consistency, Linovera® Emulsion is easy to apply on large body areas, such as limbs and feet11.

Composition

  • Hyperoxygenated fatty acids derived from sunflower oil (emollient)
  • Aloe Barbadensis extract (skin conditioning, emollient, humectant)
  • Asian Centella oil extract (skin conditioning, skin tonic, soothing agent)
  • Rosemary essential oil (organoleptic)
  • Ginkgo biloba (skin conditioning)

Indications

Linovera® Emulsion is indicated: 

  • For patients whose skin integrity is at risk
  • For prevention of pressure ulcers, vascular ulcers and diabetic foot ulcers
  • For treatment of stage 1  pressure ulcers
  • For large skin surfaces, such as whole lower limbs

Advantages

  • Enhances skin integrity12,13
  • Increases the resistance of the skin against the agents that cause pressure ulcers and other wounds12,13
  • Can prevent dehydration  of the skin14,11
  • Reduces frictional forces12
  • Can reduce the damage caused by free radicals due to antioxidant activity8,7
  • Helps to maintain skin moisture levels14,11
  • Easy to use14,11

 

1 Garraud O, Hozzein WN, Badr G. Wound healing: time to look for intelligent, 'natural' immunological approaches? BMC Immunol. 2017 Jun 21;18(Suppl 1):23. doi: 10.1186/s12865-017-0207-y. PMID: 28681702; PMCID: PMC5499069
2 Vogt TN, Koller FJ, Santos PND, Lenhani BE, Guimarães PRB, Kalinke LP. Quality of life assessment in chronic wound patients using the Wound-QoL and FLQA-Wk instruments. Invest Educ Enferm. 2020 Oct;38(3):e11. doi: 10.17533/udea.iee.v38n3e11. PMID: 33306901; PMCID: PMC7885545.
3 Armstrong DG, Tan TW, Boulton AJM, Bus SA. Diabetic Foot Ulcers: A Review. JAMA. 2023 Jul 3;330(1):62-75.
4 Schaper NC, van Netten JJ, Apelqvist J, Bus SA, Hinchliffe RJ, Lipsky BA, IWGDF Editorial Board. Practical guidelines on the prevention and management of diabetic foot disease (IWGDF 2019 update). Diabetes Metab Res Rev. 2020;36 Suppl 1:e3266. 
5 Servizo Galego de Saúde. Collection of practical guides of wounds of the Servizo Galego de Saúde: practical guide for pressure ulcers - guide no. 1. 2017; p. 1-90.
6 Lin TK, Zhong L, Santiago JL. Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils. Int J Mol Sci. 2017 Dec 27;19(1):70. doi: 10.3390/ijms19010070. PMID: 29280987; PMCID: PMC5796020.
7 Lania BG, Morari J, Almeida ARd, Silva MNd, Vieira-Damiani G, Lins KdA, César CL, Velloso LA, Maia NB, Cintra ML, Velho PENF. Topical essential fatty acid oil on wounds: Local and systemic effects. PLoS One. 2019;14(1):e0210059.
8 Torra i Bou JE, Segovia Gómez T, Verdú Soriano J, Nolasco Bonmatí A, Rueda López J, Arboix i Perejamo M. The effectiveness of a hyperoxygenated fatty acid compound in preventing pressure ulcers. J Wound Care. 2005;14(3):117-21.
9 Lázaro-Martínez JL, Sánchez-Ríos JP, García-Morales E, Cecilia-Matilla A, Segovia-Gómez T. Increased transcutaneous oxygen tension in the skin dorsum over the foot in patients with diabetic foot disease in response to the topical use of an emulsion of hyperoxygenated fatty acids. Int J Low Extrem Wounds. 2009;8(4):187-93.
10 Lupiañez-Perez I, Uttumchandani SK, Morilla-Herrera JC, Martin-Santos FJ, Fernandez-Gallego MC, Navarro-Moya FJ, Lupiañez-Perez Y, Contreras-Fernandez E, Morales-Asencio JM. Topical olive oil is not inferior to hyperoxygenated fatty aids to prevent pressure ulcers in high-risk immobilised patients in home care. Results of a multicentre randomised triple-blind controlled non-inferiority trial. PLoS One. 2015;10(4):e0122238
11 Linovera & Linovera Emulsion-PMS_09.AN2. Questionnaire Report: Informe de cuestionario de valoración de producto [Report on the product rating questionnaire]. Rubí (Barcelona), Spain: Braun Medical S.A.U. 2021. In Spanish.
12 Aloweni F, Lim M, Chua T, Tan S, Lian S, Ang S. A randomised controlled trial to evaluate the incremental effectiveness of a prophylactic dressing and fatty acids oil in the prevention of pressure injuries. Wound Practice & Research: Journal of the Australian Wound Management Association. 2017;25(1):24-34.
13 Castillo Martín B, Castillo Martín JI, Lago Oliver J, Diz Gómez J. The effect of hyperoxygenated fatty acids in preventing skin lesions caused by surgical pneumatic tourniquets. Adv Skin Wound Care. 2018;31(5):214-7.
14 Federici A, Federici G. Evaluation of the efficacy of a preparation containing essential fatty acids and plant extracts in the prevention and treatment of dehydrated skin in diabetic patients. Acta Vulnologica. 2014;12(4):177-86.