Lyoplant® Onlay
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Biological Onlay dura substitution
Lyoplant® Onlay is a biological, absorbable dura substitute consisting of a bilayer membrane, designed to provide high ease of use.
The product stands out due to the fast application, the easy handling, the versatile usage, and the reliable treatment for the patient. [1-9]
Additional information
CUT
• Lyoplant® Onlay can be cut in the required shape and size easily.
Onlay technique:
• The implant should overlap the dura defect by approx. 1 cm to ensure a high level of adhesion and a liquid-tight seal.
Suturing:
• The implant should be cut as closely as possible to the defect size.
REHYDRATE
• Ensure that the fleece-like, porous side (labeled ‘DURA SIDE’) is facing the dura.
• Which side has to face the dura should be identified before rehydration.
• Prior to implantation, Lyoplant® Onlay is placed in sterile saline solution or in another isotonic solution to ensure better suppleness and flexibility.
APPLY
Onlay technique:
• The implant simply has to be laid flat against the defect edges, ensuring that it is not taut.
Suturing:
• If required and if considered necessary by the user, Lyoplant® Onlay can be sutured in place. The implant should be fixed with non-absorbable suture material (polyester polypropylene), using atraumatic round-bodied needles.
• The implant can be sealed with fibrin glue.
Advantages
- Simple, time-saving Onlay application with the possibility to incorporate suture fixation if necessary. [1,2,4,6]
- One dura substitute for various indications. [2-5]
- High liquid tightness of the implant supports preventing CSF leakages. [1,2,4,5,9]
- High tensile strength of the implant prevents suture pull-out. [2,6,9]
- Integrates with the body’s own connective tissue cells. [1,2]
Indication
Lyoplant® Onlay is indicated for the replacement and extension of connective tissue structure in neurosurgery.
[1] Clinical trial. Neulen, A et al. Evaluation of efficacy and biocompatibility of a novel semisynthetic collagen matrix as a dural onlay graft in a large animal model. Acta Neurochirurgica. 2011 July 9; 153(11):2241-2250.
[2] Clinical trial. Greifzu F. Clinical Study report LYON study – Assessment of the performance of Lyoplant® Onlay for Duraplasty. 2019.
[3] Clinical trial. Report of a prospective, multi-center, randomized, parallel controlled clinical trial evaluating the effectiveness and safety of the absorbable onlay dura substitute Lyoplant® Onlay in dural repair. 2020.
[4] Expert Report. Bode F. Expert report – Lyoplant® Onlay. 2016.
[5] Expert Report. Nestler U. Expert report – Lyoplant® Onlay. 2015.
[6] Aesculap AG. Rasche A. Results of a Lyoplant® Onlay Evaluation Form. 2015.
[7] Aesculap AG. Test report determination of thickness, test number 2011-RB-62.
[8] Aesculap AG. Test report - Lyoplant® Onlay 180° Folding Test. 2011.
[9] Aesculap AG. Technical data Lyoplant® Onlay. 2011.